Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30687622 | 1.00 | DRD2 (0.40) | DRD2DRD3DRD4RETFAAH | |
| SCHEMBL26682796 | 0.90 | DRD2 (0.38) | DRD2DRD3DRD4RETFAAH | |
| SCHEMBL30687775 | 0.89 | PPARA (0.37) | DRD2DRD3DRD4RETFAAH | |
| SCHEMBL26682264 | 0.89 | PARP1 (0.40) | DRD2DRD3DRD4RETFAAH | |
| SCHEMBL26680619 | 0.89 | RET (0.40) | DRD2DRD3DRD4RETFAAH | |
| SCHEMBL26681380 | 0.88 | PARP1 (0.41) | DRD2DRD3DRD4FAAHPARP1 | |
| SCHEMBL26681640 | 0.88 | PARP1 (0.41) | DRD2DRD3DRD4RETFAAH | |
| SCHEMBL26680793 | 0.87 | PPARG (0.39) | DRD2DRD3PPARACHRM3PPARG | |
| SCHEMBL30687711 | 0.87 | PPARG (0.39) | DRD2DRD3PPARACHRM3PPARG | |
| SCHEMBL30687793 | 0.86 | PARP1 (0.39) | DRD2DRD3DRD4FAAHPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |