Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | BID | P55957 | 2/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26681772 | 0.90 | KMT2A (0.43) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL26681462 | 0.88 | MEN1 (0.42) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL26682872 | 0.86 | KMT2A (0.44) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL26682790 | 0.85 | CHEK1 (0.47) | DRD2DRD4DRD3PIK3CDPIK3R1 | |
| SCHEMBL26680554 | 0.84 | MEN1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL26681442 | 0.83 | MEN1 (0.47) | MEN1KMT2ADRD2DRD3MAPT | |
| SCHEMBL26681869 | 0.82 | MEN1 (0.44) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL26683121 | 0.81 | MEN1 (0.43) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL26681833 | 0.80 | OPRD1 (0.44) | DRD2DRD4DRD3PIK3CDPIK3R1 | |
| SCHEMBL26682667 | 0.80 | MEN1 (0.44) | MEN1KMT2ADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |