Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657176 | 0.86 | GCK (0.66) | GCK | |
| SCHEMBL2672036 | 0.86 | GCK (0.66) | GCK | |
| SCHEMBL4102380 | 0.83 | GCK (0.54) | GCK | |
| SCHEMBL4102382 | 0.83 | GCK (0.54) | GCK | |
| SCHEMBL2656477 | 0.81 | GCK (0.77) | GCK | |
| SCHEMBL9072585 | 0.69 | GCK (0.76) | GCK | |
| SCHEMBL14423113 | 0.69 | FFAR2 (0.56) | GCK | |
| SCHEMBL2642057 | 0.69 | FFAR2 (0.56) | GCK | |
| SCHEMBL14423112 | 0.69 | FFAR2 (0.56) | GCK | |
| SCHEMBL2642131 | 0.69 | FFAR2 (0.56) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116107-A2 | PIPERAZINE DERIVATIVES AS GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2008-09-25 | — | — | WO | disclosed |