Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668337 | 0.90 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL712707 | 0.85 | PRMT5 (0.40) | PDGFRBPDGFRAPRMT5CYP19A1CYP11B1 | |
| SCHEMBL712703 | 0.75 | PRMT5 (0.46) | PRMT5CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL711188 | 0.74 | CYP3A4 (0.41) | PRMT5MEN1KMT2A | |
| SCHEMBL712174 | 0.73 | MAPT (0.36) | PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL2668272 | 0.71 | SYK (0.34) | FGFR1PPARG | |
| SCHEMBL711177 | 0.69 | PRMT5 (0.42) | PDGFRBPDGFRAPRMT5CYP19A1CYP11B1 | |
| SCHEMBL10206538 | 0.67 | MAPT (0.42) | PDGFRBPDGFRAPRMT5 | |
| SCHEMBL10206615 | 0.63 | IKBKB (0.47) | FGFR1PRMT5CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10206607 | 0.61 | CYP3A4 (0.51) | PDGFRBPDGFRAPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028135-A2 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-08 | — | — | WO | disclosed |