Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24631023 | 0.80 | DDR1 (0.43) | PDE1BKDM4EPOLB | |
| SCHEMBL710842 | 0.80 | CYP2C9 (0.53) | SMN1; SMN2RAB9ANPC1HSD17B10CHEK2 | |
| SCHEMBL14683910 | 0.74 | DGAT1 (0.41) | SMN1; SMN2RAB9ANPC1HSD17B10PDE1B | |
| SCHEMBL690399 | 0.72 | DGAT1 (0.46) | SMN1; SMN2RAB9ANPC1HSD17B10PDE1B | |
| SCHEMBL31161564 | 0.71 | DGAT1 (0.40) | RAB9ANPC1HSD17B10PDE1BDGAT1 | |
| SCHEMBL31382642 | 0.71 | CHEK2 (0.39) | SMN1; SMN2RAB9ANPC1HSD17B10CHEK2 | |
| SCHEMBL16749497 | 0.70 | ABCB1 (0.40) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL17516281 | 0.70 | ATM (0.49) | SMN1; SMN2RAB9AHSD17B10PDE1BKDM4E | |
| SCHEMBL7713081 | 0.70 | DGAT1 (0.45) | RAB9APDE1BDGAT1KDM4EALDH1A1 | |
| SCHEMBL31457180 | 0.70 | HPGD (0.37) | PDE4APDE4BPDE4CPDE4DHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028135-A2 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-08 | — | — | WO | disclosed |