Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26683331 | 1.00 | CA12 (0.40) | CA12CA1CA2CA9MGAM | |
| SCHEMBL1155520 | 0.84 | CA12 (0.42) | CA12CA1CA2CA9MGAM | |
| SCHEMBL26684401 | 0.84 | HTT (0.39) | LGALS3ALDH1A1LMNAPTPN1CDC25B | |
| SCHEMBL26684394 | 0.84 | HTT (0.39) | LGALS3ALDH1A1LMNAPTPN1CDC25B | |
| SCHEMBL12862751 | 0.83 | CA12 (0.43) | CA12CA1CA2CA9MGAM | |
| SCHEMBL14262390 | 0.82 | CA12 (0.44) | CA12CA1CA2CA9MGAM | |
| SCHEMBL11983464 | 0.78 | CA12 (0.42) | CA12CA1CA2CA9MGAM | |
| SCHEMBL31124085 | 0.78 | CA12 (0.45) | CA12CA1CA2CA9MGAM | |
| SCHEMBL31605659 | 0.76 | LGALS3 (0.35) | CA12CA1CA2CA9LGALS3 | |
| SCHEMBL909222 | 0.72 | HTT (0.44) | CA12CA1CA2CA9MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220237-A1 | BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS | GENENTECH, INC. (US) | 2023-11-16 | — | — | WO | disclosed |