Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 15/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 15/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 15/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 10/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | AOC1 | P19801 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685261 | 0.88 | PBRM1 (0.45) | SMARCA2SMARCA4PBRM1BRD4NR1I2 | |
| SCHEMBL30632461 | 0.88 | PBRM1 (0.45) | SMARCA2SMARCA4PBRM1BRD4NR1I2 | |
| SCHEMBL26685079 | 0.82 | DPP4 (0.39) | BRD4DPP4 | |
| SCHEMBL26685057 | 0.81 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1BRD4NR1I2 | |
| SCHEMBL31570168 | 0.81 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1BRD4NR1I2 | |
| SCHEMBL31570175 | 0.81 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1BRD4NR1I2 | |
| SCHEMBL26685015 | 0.81 | SMARCA2 (0.47) | SMARCA2SMARCA4PBRM1BRD4NR1I2 | |
| SCHEMBL24461456 | 0.74 | PBRM1 (0.46) | SMARCA2SMARCA4PBRM1BRD4NR1I2 | |
| SCHEMBL24461129 | 0.73 | SMARCA2 (0.45) | SMARCA2SMARCA4PBRM1BRD4NR1I2 | |
| SCHEMBL31570167 | 0.72 | DPP4 (0.32) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119998278-A | Compounds and uses thereof | 福宏治疗公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4522278-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |