SCHEMBL26685079

SCHEMBL26685079

CC(=O)N1CC(c2cc3cc(O)nnc3cc2Cl)C1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 1/20 0.39
▸ HSP90AA1 P07900 1/20 0.32
▸ BRD4 O60885 2/20 0.31
▸ BRD3 Q15059 1/20 0.31
▸ CREBBP Q92793 1/20 0.31
▸ OPRL1 P41146 1/20 0.30
▸ SMO Q99835 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ KDM4A O75164 1/20 0.30
▸ KDM5C P41229 1/20 0.30
▸ KDM4C Q9H3R0 1/20 0.30
▸ KDM3A Q9Y4C1 1/20 0.30
▸ PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26685148 0.82 SMARCA2 (0.45) DPP4BRD4
SCHEMBL26685113 0.77 DPP4 (0.32) DPP4
SCHEMBL31570146 0.76 QDPR (0.42) BRD4KDM4EKDM4AKDM5CKDM4C
SCHEMBL26685131 0.76 QDPR (0.42) BRD4KDM4EKDM4AKDM5CKDM4C
SCHEMBL26685025 0.76 QDPR (0.42) BRD4KDM4EKDM4AKDM5CKDM4C
SCHEMBL31570183 0.76 QDPR (0.42) BRD4KDM4EKDM4AKDM5CKDM4C
SCHEMBL30632461 0.69 PBRM1 (0.45) BRD4
SCHEMBL26685261 0.69 PBRM1 (0.45) BRD4
SCHEMBL26888672 0.67 QDPR (0.59) BRD4PDE10A
SCHEMBL31570179 0.63 DPP4 (0.43) DPP4OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4522278-A1 BENZOYPARAZINE PYRAZINES ANE THEIR USES Foghorn Therapeutics Inc. (US) 2025-03-19 — — EP disclosed
WO-2023220129-A1 BENZOYPARAZINE PYRAZINES ANE THEIR USES FOGHORN THERAPEUTICS INC. (US) 2023-11-16 — — WO disclosed
WO-2023220129-A1 BENZOYPARAZINE PYRAZINES ANE THEIR USES FOGHORN THERAPEUTICS INC. (US) 2023-11-16 — — WO disclosed
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