Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543230 | 1.00 | MAPK1 (0.54) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL31543182 | 0.85 | MAPK1 (0.54) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL31543309 | 0.84 | MAPK1 (0.53) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL16110613 | 0.84 | MAPK1 (0.64) | MAPK1CDK7CLK4 | |
| SCHEMBL16110615 | 0.84 | MAPK1 (0.64) | MAPK1CDK7CLK4 | |
| SCHEMBL31543498 | 0.83 | MAPK1 (0.51) | MAPK1EGFRMAP3K5JAK1TYK2 | |
| SCHEMBL31543411 | 0.83 | MAPK1 (0.54) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL30632858 | 0.83 | MAPK1 (0.52) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL26685753 | 0.83 | MAPK1 (0.52) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL31543078 | 0.82 | MAPK1 (0.53) | MAPK1EGFRMAP3K5MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522612-A1 | TYK2 INHIBITORS | Biogen MA Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220046-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2023-11-16 | — | — | WO | disclosed |