Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685467 | 1.00 | MAPK1 (0.54) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL31543182 | 0.85 | MAPK1 (0.54) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL31543309 | 0.84 | MAPK1 (0.53) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL16110613 | 0.84 | MAPK1 (0.64) | MAPK1CDK7CLK4 | |
| SCHEMBL16110615 | 0.84 | MAPK1 (0.64) | MAPK1CDK7CLK4 | |
| SCHEMBL31543498 | 0.83 | MAPK1 (0.51) | MAPK1EGFRMAP3K5JAK1TYK2 | |
| SCHEMBL31543411 | 0.83 | MAPK1 (0.54) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL30632858 | 0.83 | MAPK1 (0.52) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL26685753 | 0.83 | MAPK1 (0.52) | MAPK1EGFRMAP3K5MAPTTSHR | |
| SCHEMBL31543078 | 0.82 | MAPK1 (0.53) | MAPK1EGFRMAP3K5MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
| CN-119654322-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | MAPK1 228/4885EGFR 380/4885MAP3K5 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.