Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1329599 | 0.82 | GCK (0.46) | GCK | |
| Hydrochloric Acid SCHEMBL1328478 | 0.81 | GCK (0.45) | GCK | |
| SCHEMBL1328997 | 0.65 | GCK (0.36) | GCK | |
| SCHEMBL1330206 | 0.62 | GCK (0.70) | GCK | |
| SCHEMBL9072486 | 0.61 | GCK (0.45) | GCK | |
| SCHEMBL15688128 | 0.60 | MEN1 (0.47) | — | |
| SCHEMBL15405751 | 0.57 | NPC1 (0.51) | — | |
| SCHEMBL24426105 | 0.56 | TSHR (0.32) | — | |
| Methyl Alcohol SCHEMBL11273876 | 0.55 | L3MBTL1 (0.66) | — | |
| SCHEMBL11864763 | 0.55 | L3MBTL1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117381-A9 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2008-03-27 | — | — | WO | disclosed |