Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241744 | 0.80 | SMYD3 (0.41) | ALDH1A1TSHRKDM4ESMYD3MAPK1 | |
| SCHEMBL12204173 | 0.80 | SMYD3 (0.41) | ALDH1A1TSHRKDM4ESMYD3MAPK1 | |
| SCHEMBL15384122 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL24429365 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL13450092 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL2668502 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRKDM4EMAPK1POLB | |
| SCHEMBL5259671 | 0.71 | — | — | |
| SCHEMBL12801234 | 0.71 | MEN1 (0.38) | ALDH1A1TSHRL3MBTL1KDM4EMEN1 | |
| SCHEMBL4668397 | 0.71 | — | — | |
| SCHEMBL2668601 | 0.70 | ALDH1A1 (0.42) | ALDH1A1TSHRL3MBTL1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377856-A1 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2011-10-19 | — | — | EP | disclosed |
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |