Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | SETD1B | Q9UPS6 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071948 | 0.88 | HDAC3 (0.39) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL2669474 | 0.86 | SETD1B (0.39) | SETD1BHDAC3CCND3HDAC4CDK6 | |
| SCHEMBL1238491 | 0.79 | CCNB2 (0.34) | GRM4CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL2669345 | 0.76 | HDAC1 (0.47) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL2668621 | 0.75 | GLS (0.46) | GRM4CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL2669443 | 0.75 | HDAC3 (0.38) | HDAC3CCND3HDAC4CDK6HDAC1 | |
| SCHEMBL2668627 | 0.73 | MAOB (0.46) | GRM4CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL2669487 | 0.72 | HDAC1 (0.47) | GRM4CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL9071934 | 0.72 | MAPK10 (0.54) | CCNB2CCNE2CDK1CDK4CCNB1 | |
| SCHEMBL9071907 | 0.71 | CCNE2 (0.35) | GRM4CCNB2CCNE2CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |