SCHEMBL26686115

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30633403	1.00	JAK2 (0.57)	JAK2KDRKITFLT3NPC1
	SCHEMBL26686359	0.89	CNR1 (0.61)	JAK2KDRKITFLT3NPC1
	SCHEMBL30633323	0.89	CNR1 (0.61)	JAK2KDRKITFLT3NPC1
	SCHEMBL26685861	0.89	JAK2 (0.56)	JAK2KDRKITFLT3NPC1
	SCHEMBL30633352	0.89	JAK2 (0.56)	JAK2KDRKITFLT3NPC1
	SCHEMBL30633305	0.89	KDR (0.57)	JAK2KDRKITFLT3NPC1
	SCHEMBL26686045	0.89	KDR (0.57)	JAK2KDRKITFLT3NPC1
	SCHEMBL30633384	0.87	JAK2 (0.62)	JAK2KDRKITFLT3DYRK1A
	SCHEMBL26685947	0.87	JAK2 (0.62)	JAK2KDRKITFLT3DYRK1A
	SCHEMBL30633331	0.86	JAK2 (0.56)	JAK2KDRDYRK1ACNR1PLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.