Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.57 |
| ▸ | KDR | P35968 | 12/20 | 0.53 |
| ▸ | KIT | P10721 | 4/20 | 0.53 |
| ▸ | FLT3 | P36888 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.51 |
| ▸ | WNT1 | P04628 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 3/20 | 0.48 |
| ▸ | FYN | P06241 | 3/20 | 0.48 |
| ▸ | CSF1R | P07333 | 3/20 | 0.48 |
| ▸ | LYN | P07948 | 3/20 | 0.48 |
| ▸ | FLT1 | P17948 | 3/20 | 0.48 |
| ▸ | FLT4 | P35916 | 3/20 | 0.48 |
| ▸ | BLK | P51451 | 3/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686115 | 1.00 | JAK2 (0.57) | JAK2KDRKITFLT3NPC1 | |
| SCHEMBL26686359 | 0.89 | CNR1 (0.61) | JAK2KDRKITFLT3NPC1 | |
| SCHEMBL30633323 | 0.89 | CNR1 (0.61) | JAK2KDRKITFLT3NPC1 | |
| SCHEMBL26685861 | 0.89 | JAK2 (0.56) | JAK2KDRKITFLT3NPC1 | |
| SCHEMBL30633352 | 0.89 | JAK2 (0.56) | JAK2KDRKITFLT3NPC1 | |
| SCHEMBL30633305 | 0.89 | KDR (0.57) | JAK2KDRKITFLT3NPC1 | |
| SCHEMBL26686045 | 0.89 | KDR (0.57) | JAK2KDRKITFLT3NPC1 | |
| SCHEMBL30633384 | 0.87 | JAK2 (0.62) | JAK2KDRKITFLT3DYRK1A | |
| SCHEMBL26685947 | 0.87 | JAK2 (0.62) | JAK2KDRKITFLT3DYRK1A | |
| SCHEMBL30633331 | 0.86 | JAK2 (0.56) | JAK2KDRDYRK1ACNR1PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | claimed |
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |