Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 4/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241591 | 1.00 | CCNE1 (0.41) | CCNE1CDK2CCNE2ITKLMNA | |
| SCHEMBL2658560 | 0.96 | ITK (0.41) | CCNE1CDK2CCNE2ITKLMNA | |
| SCHEMBL2658557 | 0.96 | ITK (0.41) | CCNE1CDK2CCNE2ITKLMNA | |
| SCHEMBL12204050 | 0.92 | NPC1 (0.42) | CCNE1CDK2CCNE2LMNACCNB2 | |
| SCHEMBL1240727 | 0.91 | CCNE1 (0.51) | CCNE1CDK2CCNE2ITKCCNB2 | |
| SCHEMBL1240730 | 0.91 | CCNE1 (0.51) | CCNE1CDK2CCNE2ITKCCNB2 | |
| SCHEMBL1241539 | 0.90 | CDK2 (0.41) | CCNE1CDK2CCNE2ITKCCNB2 | |
| SCHEMBL1241215 | 0.90 | CCNE1 (0.42) | CCNE1CDK2CCNE2ITKCCNB2 | |
| SCHEMBL2668703 | 0.90 | CCNE1 (0.42) | CCNE1CDK2CCNE2ITKCCNB2 | |
| SCHEMBL2668609 | 0.89 | ROCK2 (0.44) | CCNE1CDK2CCNE2ITKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |