⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685924 | 0.93 | CRBN (0.36) | — | |
| SCHEMBL29749877 | 0.84 | — | — | |
| SCHEMBL1502960 | 0.84 | CRBN (0.42) | — | |
| SCHEMBL29749828 | 0.84 | CRBN (0.52) | — | |
| SCHEMBL2774682 | 0.78 | CRBN (0.32) | — | |
| SCHEMBL3397460 | 0.78 | — | — | |
| SCHEMBL1786726 | 0.78 | — | — | |
| SCHEMBL2169285 | 0.78 | CRBN (0.41) | — | |
| SCHEMBL29749879 | 0.78 | CRBN (0.50) | — | |
| Hydrochloric Acid SCHEMBL6975774 | 0.76 | CRBN (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243222-A1 | PYRIMIDINE BASED MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| WO-2025106905-A1 | COMBINATION THERAPIES WITH A KRAS MODULATOR AND AN IMMUNOMODULATOR INHIBITOR | QUANTA THERAPEUTICS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| WO-2025106901-A1 | COMBINATION CANCER THERAPIES WITH A KRAS MODULATOR AND AN RTK-MAPK PATHWAY INHIBITOR | QUANTA THERAPEUTICS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| EP-4532494-A1 | PYRIMIDINE BASED MODULATORS AND USES THEREOF | Quanta Therapeutics, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119604501-A | Pyrimidine-based modulators and uses thereof | 光达治疗公司 | 2025-03-11 | — | — | CN | disclosed |
| US-12145947-B2 | Pyrimidine based modulators and uses thereof | QUANTA THERAPEUTICS, INC. (US) | 2024-11-19 | — | — | US | disclosed |
| US-20240199650-A1 | PYRIMIDINE BASED MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. | 2024-06-20 | — | — | US | disclosed |
| WO-2023230190-A1 | PYRIMIDINE BASED MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| CN-111943946-B | Dihydroquinazinone carboxylic acid compound containing nitrogen heterocyclic segment and application thereof | 中国医学科学院医药生物技术研究所 | 2022-07-01 | — | — | CN | disclosed |