Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15056759 | 0.97 | CRBN (0.30) | CRBN | |
| SCHEMBL537099 | 0.97 | ALDH1A1 (0.33) | CRBNTRIM24TRIM33 | |
| Bromide SCHEMBL5789681 | 0.94 | ALDH1A1 (0.32) | TRIM24TRIM33 | |
| SCHEMBL1786726 | 0.94 | — | — | |
| SCHEMBL2775678 | 0.94 | TRIM24 (0.37) | CRBNTRIM24TRIM33 | |
| SCHEMBL3397460 | 0.94 | — | — | |
| SCHEMBL3815762 | 0.91 | TRIM24 (0.40) | CRBNTRIM24TRIM33 | |
| SCHEMBL3389316 | 0.91 | — | — | |
| SCHEMBL8837715 | 0.91 | TRIM24 (0.40) | CRBNTRIM24TRIM33 | |
| SCHEMBL3400810 | 0.91 | TRIM24 (0.40) | CRBNTRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151112-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR | 주식회사 티움바이오 | 2024-07-18 | — | — | WO | disclosed |
| CN-118063308-A | Preparation method of 5- (1-cyclopentenyl) valeric acid | 浙江医药股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | NATIONAL SCIENCE FOUNDATION | 2021-01-14 | — | — | US | disclosed |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2019-10-17 | — | — | US | disclosed |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-03-26 | — | — | US | disclosed |
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | NATIONAL SCIENCE FOUNDATION | 2017-06-08 | — | — | US | disclosed |
| US-9388131-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150329567-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-11-19 | — | — | US | disclosed |
| US-9012658-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-21 | — | — | US | disclosed |
| US-8791288-B2 | Acid-labile ester monomer having spirocyclic structure, polymer, resist composition, and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-07-29 | — | — | US | disclosed |
| US-8791288-B2 | Acid-labile ester monomer having spirocyclic structure, polymer, resist composition, and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-07-29 | — | — | US | disclosed |
| WO-2013179049-A1 | SPIRO DERIVATIVES AS VOLTAGE - GATED SODIUM CHANNEL MODULATORS | Convergence Pharmaceuticals Limited (GB) | 2013-12-05 | — | — | WO | disclosed |
| WO-2012149182-A2 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-11-01 | — | — | WO | disclosed |
| US-20100304295-A1 | ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-02 | — | — | US | disclosed |
| US-20100304295-A1 | ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-02 | — | — | US | disclosed |
| US-20100304295-A1 | ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-02 | — | — | US | disclosed |
| US-5043479-A | Reducing agents for ketones | ALDRICH CHEMICAL COMPANY, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| US-4866181-A | REDUCING KETONES USING (MONO- OR DI-)ISOPINOCAMPHEYL HALBORANE AS REDUCING AGENTS | ALDRICH-BORANES, INC. (US) | 1989-09-12 | — | — | US | disclosed |
| US-4772752-A | Mono- and diisopinocampheylhaloboranes as new chiral reducing agents | ALDRICH-BORANES, INC. (US) | 1988-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329567-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | BTD, POLL, POLR1A | CRBN 1094/4885TRIM24 2312/4885TRIM33 3671/4885 |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | CRBN 1094/4885TRIM24 2312/4885TRIM33 3671/4885 |
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | CRBN 1094/4885TRIM24 2312/4885TRIM33 3671/4885 |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | CRBN 1094/4885TRIM24 2312/4885TRIM33 3671/4885 |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | CRBN 1094/4885TRIM24 2312/4885TRIM33 3671/4885 |
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | BTD, POLL, POLR1A | CRBN 1094/4885TRIM24 2312/4885TRIM33 3671/4885 |
| US-20100304295-A1 | ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS | COASY, DHCR24, HCAR1 | CRBN 1308/4885TRIM24 3154/4885TRIM33 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.