SCHEMBL26686302

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30633358	1.00	JAK2 (0.46)	JAK2JAK1MAPK1PLK4AURKB
	SCHEMBL26686360	0.88	KDR (0.52)	JAK2JAK1MAPK1MAPTKDR
	SCHEMBL30633321	0.88	KDR (0.52)	JAK2JAK1MAPK1MAPTKDR
	SCHEMBL26686141	0.85	JAK2 (0.45)	JAK2JAK1MAPK1DYRK1ACYP3A4
	SCHEMBL30633313	0.85	JAK2 (0.45)	JAK2JAK1MAPK1DYRK1ACYP3A4
	SCHEMBL30633312	0.85	JAK2 (0.45)	JAK2JAK1MAPK1DYRK1ASMN1; SMN2
	SCHEMBL30633352	0.83	JAK2 (0.56)	JAK2JAK1MAPK1PLK4AURKB
	SCHEMBL31240315	0.83	MAPK1 (0.56)	JAK2MAPK1PLK4AURKBGSK3A
	SCHEMBL26685764	0.83	MAPK1 (0.56)	JAK2MAPK1PLK4AURKBGSK3A
	SCHEMBL26685861	0.83	JAK2 (0.56)	JAK2JAK1MAPK1PLK4AURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.