SCHEMBL26686403

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26686081	0.88	MAPK14 (0.53)	JAK2PDPK1AURKATGFBR1ROCK1
	SCHEMBL31240888	0.88	JAK2 (0.50)	JAK2PDPK1AURKATGFBR1ROCK1
	SCHEMBL30633334	0.88	MAPK14 (0.53)	JAK2PDPK1AURKATGFBR1ROCK1
	SCHEMBL26685977	0.88	JAK2 (0.50)	JAK2PDPK1AURKATGFBR1ROCK1
	SCHEMBL26686055	0.84	DYRK1A (0.52)	DYRK1AWNT1
	SCHEMBL30633289	0.84	DYRK1A (0.52)	DYRK1AWNT1
	SCHEMBL26685950	0.82	DYRK1A (0.51)	JAK2DYRK1AWNT1
	SCHEMBL31420125	0.82	DYRK1A (0.51)	JAK2DYRK1AWNT1
	SCHEMBL26686529	0.81	CDC7 (0.45)	PDPK1AURKATGFBR1ROCK1AURKB
	SCHEMBL31240358	0.79	ULK1 (0.61)	JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.