Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979379 | 0.87 | MAPT (0.55) | MAPTNPC1GAARAB9AL3MBTL1 | |
| SCHEMBL6987618 | 0.86 | MAPT (0.54) | MAPTNPC1GAARAB9AL3MBTL1 | |
| SCHEMBL4727973 | 0.85 | MAPT (0.53) | MAPTNPC1GAARAB9AL3MBTL1 | |
| SCHEMBL6985505 | 0.84 | MAPT (0.73) | MAPTNPC1GAARAB9AL3MBTL1 | |
| SCHEMBL6983248 | 0.83 | MAPT (0.51) | MAPTNPC1GAARAB9AL3MBTL1 | |
| SCHEMBL9612675 | 0.81 | MAOB (0.52) | MAPTNPC1GAARAB9AMAOB | |
| SCHEMBL6977065 | 0.81 | MAOB (0.47) | MAPTNPC1GAARAB9AMAOB | |
| SCHEMBL26688244 | 0.80 | ALDH1A1 (0.44) | RAB9AL3MBTL1MAOBALDH1A1POLB | |
| SCHEMBL16345194 | 0.79 | MAOB (0.47) | MAPTGAAMAOBALDH1A1HTT | |
| SCHEMBL29592689 | 0.77 | POLB (0.52) | MAPTNPC1GAARAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119136840-A | Camptothecine derivative and ligand-medicine conjugate | 海南先声再明医药股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2023217227-A1 | CAMPTOTHECIN DERIVATIVE AND LIGAND-DRUG CONJUGATE | 先声再明医药有限公司 | 2023-11-16 | — | — | WO | disclosed |