Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17327639 | 0.92 | LPAR3 (0.37) | PLA2G2ACYP3A4LPAR3LPAR1LPAR2 | |
| SCHEMBL25584062 | 0.90 | LPAR3 (0.40) | PLA2G2ACYP3A4LPAR3LPAR1LPAR2 | |
| SCHEMBL26460406 | 0.88 | LPAR3 (0.36) | CYP3A4LPAR3LPAR1LPAR2TSHR | |
| SCHEMBL26334857 | 0.85 | CYP2D6 (0.39) | CYP3A4LPAR3LPAR1LPAR2CYP2D6 | |
| SCHEMBL26334849 | 0.83 | CYP2D6 (0.42) | CYP3A4LPAR3LPAR1LPAR2CYP2D6 | |
| SCHEMBL26334850 | 0.83 | CYP2D6 (0.42) | CYP3A4LPAR3LPAR1LPAR2CYP2D6 | |
| SCHEMBL26334858 | 0.83 | CYP2D6 (0.42) | CYP3A4LPAR3LPAR1LPAR2CYP2D6 | |
| SCHEMBL22193586 | 0.80 | LPAR3 (0.40) | LPAR3LPAR1LPAR2TSHRCYP2D6 | |
| SCHEMBL19663781 | 0.80 | — | — | |
| SCHEMBL19699812 | 0.79 | CYP3A4 (0.41) | PLA2G2ACYP3A4LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230366885-A1 | DNA CONSTRUCTS, RECOMBINANT CELLS COMPRISING THEREOF, BACTERIAL PROBES, METHODS FOR THEIR PREPARATION, AND METHOD OF USING THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-11-16 | — | — | US | disclosed |
| US-20230348970-A1 | FUNCTIONALIZED NANOSTRUCTURES AND FLOW CELL DEPRESSIONS | ILLUMINA, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348970-A1 | FUNCTIONALIZED NANOSTRUCTURES AND FLOW CELL DEPRESSIONS | ILLUMINA, INC. | 2023-11-02 | — | — | US | disclosed |