SCHEMBL17327639

SCHEMBL17327639

C#CCCCCOP(=O)(O)OC

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LPAR3 Q9UBY5 6/20 0.37
▸ LPAR2 Q9HBW0 5/20 0.37
▸ LPAR1 Q92633 4/20 0.37
▸ CYP2D6 P10635 7/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ CYP3A4 P08684 4/20 0.33
▸ PLA2G2A P14555 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25584062 0.98 LPAR3 (0.40) LPAR3LPAR2LPAR1CYP2D6CYP1A2
SCHEMBL26688599 0.92 PLA2G2A (0.37) LPAR3LPAR2LPAR1CYP2D6CYP1A2
SCHEMBL26334857 0.88 CYP2D6 (0.39) LPAR3LPAR2LPAR1CYP2D6CYP1A2
SCHEMBL26334849 0.86 CYP2D6 (0.42) LPAR3LPAR2LPAR1CYP2D6CYP1A2
SCHEMBL26334858 0.86 CYP2D6 (0.42) LPAR3LPAR2LPAR1CYP2D6CYP1A2
SCHEMBL26334850 0.86 CYP2D6 (0.42) LPAR3LPAR2LPAR1CYP2D6CYP1A2
SCHEMBL22193586 0.84 LPAR3 (0.40) LPAR3LPAR2LPAR1CYP2D6CYP1A2
SCHEMBL16417850 0.82 LPAR3 (0.47) LPAR3LPAR2LPAR1CYP2D6CYP1A2
SCHEMBL14816068 0.81 BTN3A1 (0.44) LPAR3LPAR2LPAR1CYP2D6CYP1A2
SCHEMBL12091539 0.81 SAT1 (0.44) LPAR3LPAR2LPAR1CYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026421-A1 METHODS FOR CAPTURING LONG POLYNUCLEOTIDES FOR SEQUENCING SPECIFIC GENOMIC REGIONS GENERATION BIOTECH, LLC (US) 2024-01-25 — — US disclosed
US-20240026421-A1 METHODS FOR CAPTURING LONG POLYNUCLEOTIDES FOR SEQUENCING SPECIFIC GENOMIC REGIONS GENERATION BIOTECH, LLC (US) 2024-01-25 — — US disclosed
US-11821023-B2 Method for capturing long polynucleotides for sequencing specific gnomic regions GENERATION BIOTECH, LLC (US) 2023-11-21 — — US disclosed
US-11821023-B2 Method for capturing long polynucleotides for sequencing specific gnomic regions GENERATION BIOTECH, LLC (US) 2023-11-21 — — US disclosed
US-20230366885-A1 DNA CONSTRUCTS, RECOMBINANT CELLS COMPRISING THEREOF, BACTERIAL PROBES, METHODS FOR THEIR PREPARATION, AND METHOD OF USING THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-16 — — US disclosed
US-11639929-B2 Universal histidine-tag binding compounds and methods of use thereof as fluorescent probes and sensors YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-05-02 — — US disclosed
US-20180057870-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION Roche Sequencing Solutions, Inc. 2018-03-01 — — US disclosed
US-20170114341-A1 POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS BRADSHAW CURT W (US) 2017-04-27 — — US disclosed
WO-2015188197-A2 POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS SOLSTICE BIOLOGICS, LTD. (IE) 2015-12-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11639929-B2 Universal histidine-tag binding compounds and methods of use thereof as fluorescent probes and sensors HCLS1, PHF6, PHPT1 LPAR3 4564/4885LPAR2 4740/4885LPAR1 4548/4885
US-20180057870-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION PHAX, POLRMT, POLN LPAR3 3474/4885LPAR2 3499/4885LPAR1 3376/4885
US-20170114341-A1 POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS HNRNPC, RNASE1, NSUN3 LPAR3 3097/4885LPAR2 3879/4885LPAR1 4093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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