Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26887345 | 0.86 | SPHK1 (0.62) | SPHK1S1PR1S1PR2S1PR3LPAR2 | |
| SCHEMBL29496372 | 0.86 | SPHK1 (0.53) | SPHK1S1PR1S1PR2S1PR3LPAR2 | |
| Hydrochloric Acid SCHEMBL26690798 | 0.85 | SPHK1 (0.61) | SPHK1S1PR1S1PR2S1PR3LPAR2 | |
| SCHEMBL26690971 | 0.83 | SPHK1 (0.53) | SPHK1S1PR1S1PR2S1PR3LPAR2 | |
| SCHEMBL26691005 | 0.81 | SPHK1 (0.59) | SPHK1S1PR1S1PR2S1PR3LPAR2 | |
| SCHEMBL15176282 | 0.81 | SPHK1 (0.61) | SPHK1S1PR1S1PR2S1PR3LPAR2 | |
| SCHEMBL26691013 | 0.81 | SPHK1 (0.61) | SPHK1S1PR1S1PR2S1PR3LPAR2 | |
| SCHEMBL23588257 | 0.81 | SPHK1 (0.58) | SPHK1S1PR1S1PR2S1PR3LPAR2 | |
| SCHEMBL3264894 | 0.81 | SPHK1 (0.67) | SPHK1S1PR1S1PR2S1PR3LPAR2 | |
| SCHEMBL26690939 | 0.80 | SPHK1 (0.60) | SPHK1S1PR1S1PR2S1PR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373937-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373937-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | SPNS2, SPCS2, SMN1; SMN2 | SPHK1 491/4885S1PR1 610/4885S1PR2 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.