Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107442 | 0.78 | NPY5R (0.63) | NPY5RCCR5KDM4EOPRK1CYP2D6 | |
| SCHEMBL1861999 | 0.78 | NPY5R (0.63) | NPY5RCCR5KDM4EOPRK1CYP2D6 | |
| SCHEMBL2652609 | 0.78 | NPY5R (0.63) | NPY5RCCR5KDM4EOPRK1CYP2D6 | |
| SCHEMBL6180303 | 0.73 | HPGD (0.33) | KDM4EHPGDLMNA | |
| SCHEMBL2669016 | 0.71 | — | — | |
| SCHEMBL2668110 | 0.68 | NPY5R (0.43) | NPY5RCCR5OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL1107504 | 0.68 | CA2 (0.48) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL12593796 | 0.67 | POLB (0.42) | LMNA | |
| SCHEMBL835376 | 0.66 | KDM4E (0.48) | KDM4EALDH1A1MAPTADRA2AADRA2C | |
| SCHEMBL14285930 | 0.65 | GAA (0.48) | NPY5RCCR5KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051847-A1 | TRICYCLO SUBSTITUTED AMIDES AS GLUCOKINASE MODULATORS | PROSIDION LTD (GB) | 2007-05-10 | — | — | WO | disclosed |