Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915461 | 1.00 | PIK3CA (0.39) | PIK3CAGABRG2GABRB3GABRA2MTOR | |
| SCHEMBL4915466 | 1.00 | PIK3CA (0.39) | PIK3CAGABRG2GABRB3GABRA2MTOR | |
| SCHEMBL13991075 | 1.00 | PIK3CA (0.39) | PIK3CAGABRG2GABRB3GABRA2MTOR | |
| SCHEMBL2660996 | 0.92 | PIK3CA (0.42) | PIK3CAGABRG2GABRB3GABRA2MTOR | |
| SCHEMBL2658060 | 0.90 | PIK3CA (0.45) | PIK3CAGABRG2GABRB3GABRA2MTOR | |
| SCHEMBL2660827 | 0.90 | PIK3CA (0.47) | PIK3CAGABRG2GABRB3GABRA2MTOR | |
| SCHEMBL13991074 | 0.83 | GABRG2 (0.34) | GABRG2GABRB3GABRA2NPY1RNPY5R | |
| SCHEMBL8103339 | 0.83 | GABRG2 (0.34) | GABRG2GABRB3GABRA2NPY1RNPY5R | |
| SCHEMBL4916839 | 0.83 | GABRG2 (0.34) | GABRG2GABRB3GABRA2NPY1RNPY5R | |
| SCHEMBL4916846 | 0.83 | GABRG2 (0.34) | GABRG2GABRB3GABRA2NPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155572-A2 | FUSED QUINOLINE DERIVATIVES USEFUL AS GABA MODULATORS | ASTRAZENECA AB (SE) | 2008-12-24 | — | — | WO | disclosed |