Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644054 | 0.93 | TSHR (0.40) | CXCR2PRKAA2MAPTCXCR1TSHR | |
| SCHEMBL2664043 | 0.83 | MAPT (0.40) | PRKAA2MAPTTSHR | |
| SCHEMBL2643521 | 0.82 | TSHR (0.41) | PRKAA2MAPTTSHRBDKRB1 | |
| SCHEMBL2643419 | 0.82 | TSHR (0.41) | PRKAA2MAPTTSHRBDKRB1 | |
| SCHEMBL2643416 | 0.82 | TSHR (0.41) | PRKAA2MAPTTSHRBDKRB1 | |
| SCHEMBL2643590 | 0.81 | MAPT (0.40) | PRKAA2MAPTTSHR | |
| SCHEMBL2643593 | 0.81 | MAPT (0.40) | PRKAA2MAPTTSHR | |
| SCHEMBL2644105 | 0.79 | MAPT (0.46) | PRKAA2MAPTTSHRLMNA | |
| SCHEMBL2643618 | 0.78 | MAPT (0.40) | MAPTTSHRL3MBTL1LMNADEGS1 | |
| SCHEMBL2644546 | 0.77 | WNT3A (0.41) | PRKAA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053503-A1 | SUBSTITUTED DIHYDROISOINDOLONES AS ALLOSTERIC MODULATORS OF GLUCOKINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-10 | — | — | WO | disclosed |