Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.42 |
| ▸ | ABL1 | P00519 | 6/20 | 0.41 |
| ▸ | SRC | P12931 | 6/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.39 |
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | HCK | P08631 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | MTOR | P42345 | 5/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 5/20 | 0.39 |
| ▸ | PRKDC | P78527 | 5/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.39 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22504974 | 0.84 | PIK3CD (0.46) | PIK3CDABL1SRCPIK3CGPIK3R1 | |
| SCHEMBL29641490 | 0.84 | PIK3CD (0.46) | PIK3CDABL1SRCPIK3CGPIK3R1 | |
| SCHEMBL24494672 | 0.83 | PIK3CD (0.45) | PIK3CDABL1SRCPIK3CGPIK3R1 | |
| SCHEMBL29641509 | 0.82 | PIK3CD (0.44) | PIK3CDABL1SRCPIK3CGPIK3R1 | |
| SCHEMBL22504971 | 0.82 | PIK3CD (0.44) | PIK3CDABL1SRCPIK3CGPIK3R1 | |
| SCHEMBL16783404 | 0.74 | PIK3CD (0.50) | PIK3CDABL1SRCPIK3CGPIK3R1 | |
| SCHEMBL16783667 | 0.74 | PIK3CD (0.51) | PIK3CDABL1SRCPIK3CGPIK3R1 | |
| SCHEMBL16783837 | 0.74 | PIK3CD (0.55) | PIK3CDABL1SRCPIK3CGPIK3R1 | |
| SCHEMBL16806468 | 0.73 | PIK3CD (0.53) | PIK3CDABL1SRCPIK3CGPIK3R1 | |
| SCHEMBL16783537 | 0.73 | PIK3CD (0.53) | PIK3CDABL1SRCPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947384-B1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2023-11-01 | — | — | EP | disclosed |