Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.44 |
| ▸ | SRC | P12931 | 6/20 | 0.42 |
| ▸ | ABL1 | P00519 | 5/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | PRKDC | P78527 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | HCK | P08631 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 3/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22504971 | 1.00 | PIK3CD (0.44) | PIK3CDSRCABL1PIK3CGPIK3R1 | |
| SCHEMBL24494672 | 0.92 | PIK3CD (0.45) | PIK3CDSRCABL1PIK3CGPIK3R1 | |
| SCHEMBL16783471 | 0.89 | PIK3CD (0.45) | PIK3CDSRCABL1PIK3CGPIK3R1 | |
| SCHEMBL16783451 | 0.88 | SRC (0.48) | PIK3CDSRCABL1PIK3CGPIK3R1 | |
| SCHEMBL16783414 | 0.87 | PIK3CD (0.44) | PIK3CDSRCABL1PIK3CGPIK3R1 | |
| SCHEMBL29641490 | 0.85 | PIK3CD (0.46) | PIK3CDSRCABL1PIK3CGPIK3R1 | |
| SCHEMBL22504974 | 0.85 | PIK3CD (0.46) | PIK3CDSRCABL1PIK3CGPIK3R1 | |
| SCHEMBL22498306 | 0.82 | PIK3CD (0.41) | PIK3CDSRCABL1PIK3CGPIK3R1 | |
| SCHEMBL16783796 | 0.82 | PIK3CD (0.42) | PIK3CDSRCABL1PIK3CGPIK3R1 | |
| SCHEMBL26695707 | 0.82 | PIK3CD (0.42) | PIK3CDSRCABL1PIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12527797-B2 | Isochromene derivatives as phosphoinositide 3-kinases inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2026-01-20 | — | — | US | disclosed |
| US-20220175784-A1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175784-A1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | PIKFYVE, PDPK1, PIK3R5 | PIK3CD 5/4885SRC 157/4885ABL1 136/4885 |
| US-12527797-B2 | Isochromene derivatives as phosphoinositide 3-kinases inhibitors | PIK3R5, PIK3CD, PIK3R4 | PIK3CD 2/4885SRC 190/4885ABL1 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.