Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669712 | 1.00 | GCK (0.63) | GCKKCNH2HRH3 | |
| SCHEMBL2075151 | 0.88 | GCK (0.65) | GCKKCNH2HRH3 | |
| SCHEMBL2074382 | 0.88 | GCK (0.65) | GCKKCNH2HRH3 | |
| SCHEMBL2657666 | 0.88 | GCK (0.65) | GCKKCNH2HRH3 | |
| SCHEMBL2074914 | 0.86 | GCK (0.63) | GCKKCNH2HRH3 | |
| SCHEMBL2072767 | 0.86 | GCK (0.63) | GCKKCNH2HRH3 | |
| SCHEMBL2075677 | 0.86 | GCK (0.63) | GCKKCNH2HRH3 | |
| SCHEMBL2656738 | 0.86 | GCK (0.63) | GCKKCNH2HRH3 | |
| SCHEMBL2075054 | 0.86 | GCK (0.62) | GCKKCNH2HRH3 | |
| SCHEMBL2072486 | 0.86 | GCK (0.65) | GCKKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050101-A2 | BENZOYL AMINO HETEROCYCLYL COMPOUNDS USEFUL IN THE TREATMENT OF A DISEASE MEDIATED THROUGH GLK | ASTRAZENECA AB (SE) | 2008-05-02 | — | — | WO | disclosed |