Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.40 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22413208 | 0.86 | KCNN3 (0.58) | KCNN3GSK3BMEN1KMT2AKCNN1 | |
| SCHEMBL22413144 | 0.84 | KCNN3 (0.48) | KCNN3GSK3BKCNN1KCNN2 | |
| SCHEMBL18051111 | 0.83 | KCNN3 (0.64) | KCNN3MAPK1MAPTMEN1KMT2A | |
| SCHEMBL30872083 | 0.79 | KCNN3 (0.49) | KCNN3GSK3BMEN1KMT2AKCNN1 | |
| SCHEMBL12954018 | 0.78 | CDK2 (0.52) | KCNN3GSK3BMEN1KMT2AKCNN1 | |
| SCHEMBL30083511 | 0.77 | KCNN3 (0.42) | KCNN3GSK3BMEN1KMT2AKCNN1 | |
| SCHEMBL26697079 | 0.77 | KCNN3 (0.42) | KCNN3POLBMAPK1MAPTMEN1 | |
| SCHEMBL30083523 | 0.77 | KCNN3 (0.44) | KCNN3GSK3BMAPTMEN1KMT2A | |
| SCHEMBL30083401 | 0.75 | GSK3B (0.45) | KCNN3GSK3BMEN1KMT2AKCNN1 | |
| SCHEMBL30083536 | 0.75 | BRD4 (0.49) | KCNN3GSK3BKCNN1KCNN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |