Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.56 |
| ▸ | CDK9 | P50750 | 10/20 | 0.56 |
| ▸ | CDK7 | P50613 | 10/20 | 0.44 |
| ▸ | CCNH | P51946 | 10/20 | 0.44 |
| ▸ | MNAT1 | P51948 | 10/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26696720 | 0.89 | CDK2 (0.45) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL21482000 | 0.84 | CDK9 (0.43) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL21482005 | 0.82 | CDK9 (0.40) | CDK2CDK9 | |
| SCHEMBL30716199 | 0.80 | CKS1B (0.43) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL18073080 | 0.78 | CDK2 (0.75) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL18073082 | 0.77 | CDK9 (0.56) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL26697094 | 0.76 | CDK2 (0.69) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL26697105 | 0.76 | CDK2 (0.51) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL23351749 | 0.75 | CDK7 (0.43) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL18073059 | 0.75 | CDK9 (0.73) | CDK2CDK9CDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |