Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423126 | 1.00 | GCK (0.52) | GCKKCNH2CYP1A2ABCB1CYP3A4 | |
| SCHEMBL428559 | 0.95 | GCK (0.58) | GCKKCNH2CYP1A2ABCB1CYP3A4 | |
| SCHEMBL426008 | 0.88 | GCK (0.54) | GCKKCNH2 | |
| SCHEMBL424270 | 0.87 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL462995 | 0.87 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL424513 | 0.85 | GCK (0.60) | GCKKCNH2 | |
| SCHEMBL428556 | 0.84 | GCK (0.48) | GCKKCNH2CYP1A2ABCB1CYP3A4 | |
| SCHEMBL1056454 | 0.82 | GCK (0.52) | GCKKCNH2CYP1A2ABCB1CYP3A4 | |
| SCHEMBL1055145 | 0.81 | GCK (0.47) | GCKKCNH2CYP1A2ABCB1CYP3A4 | |
| SCHEMBL3463240 | 0.81 | GCK (0.47) | GCKKCNH2CYP1A2ABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099080-A1 | NOVEL PHENYLPYRROLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-08-13 | — | — | WO | disclosed |