Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 9/20 | 0.48 |
| ▸ | GCGR | P47871 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718932 | 0.79 | GCGR (0.49) | GCGGCGRHDAC6GAA | |
| SCHEMBL2669985 | 0.77 | GCGR (0.47) | GCGGCGR | |
| SCHEMBL721582 | 0.75 | GCGR (0.46) | GCGGCGRHDAC6GAA | |
| SCHEMBL2669917 | 0.74 | GCGR (0.43) | GCGGCGR | |
| SCHEMBL2669876 | 0.72 | GCGR (0.47) | GCGGCGRHDAC6 | |
| SCHEMBL2669757 | 0.72 | GCGR (0.63) | GCGGCGR | |
| SCHEMBL2669988 | 0.71 | GCGR (0.43) | GCGGCGR | |
| SCHEMBL721583 | 0.68 | GCG (0.42) | GCGGCGRHDAC6GAAMEN1 | |
| SCHEMBL21545006 | 0.66 | GCGR (0.53) | GCGGCGR | |
| SCHEMBL21545024 | 0.66 | GCGR (0.53) | GCGGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |