SCHEMBL2669985

SCHEMBL2669985

CCCC(CCC)C(Nc1ccc(C(=O)NCCC(=O)O)cc1)c1nn(-c2ccccc2)c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GCGR P47871 12/20 0.47
GCG P01275 9/20 0.42
GLP1R P43220 1/20 0.40
GIPR P48546 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9070785 0.86 GCG (0.43) GCGRGCG
SCHEMBL2669917 0.84 GCGR (0.43) GCGRGCG
SCHEMBL719688 0.78 GCGR (0.47) GCGRGCGGLP1RGIPR
SCHEMBL2669798 0.77 GCG (0.48) GCGRGCG
SCHEMBL2669876 0.75 GCGR (0.47) GCGRGCG
SCHEMBL2669757 0.74 GCGR (0.63) GCGRGCG
SCHEMBL2669988 0.73 GCGR (0.43) GCGRGCG
SCHEMBL2669986 0.72 GCG (0.40) GCG
SCHEMBL13069224 0.68 GCG (0.44) GCGRGCGGLP1RGIPR
SCHEMBL718054 0.66 GCGR (0.58) GCGRGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009110520-A1 HETEROCYCLIC COMPOUND 武田薬品工業株式会社 (JP) 2009-09-11 WO disclosed