⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698139 | 1.00 | — | — | |
| SCHEMBL26902322 | 0.83 | TSHR (0.34) | — | |
| SCHEMBL30103422 | 0.83 | TSHR (0.34) | — | |
| SCHEMBL30103398 | 0.81 | EPHX2 (0.31) | — | |
| SCHEMBL26902321 | 0.78 | EPHX2 (0.32) | — | |
| SCHEMBL26879571 | 0.78 | EPHX2 (0.35) | — | |
| SCHEMBL19546261 | 0.77 | LMNA (0.35) | — | |
| SCHEMBL26879569 | 0.77 | EPHX2 (0.34) | — | |
| SCHEMBL26879609 | 0.77 | EPHX2 (0.38) | — | |
| SCHEMBL26879607 | 0.77 | EPHX2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346951-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | YALE UNIVERSITY | 2023-11-02 | — | — | US | disclosed |