Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698267 | 0.87 | CHRM3 (0.52) | CHRM3MEN1KMT2ACHRM1CHRM4 | |
| SCHEMBL7592805 | 0.86 | CHRM3 (0.57) | CHRM3 | |
| SCHEMBL3043721 | 0.84 | CYP2B6 (0.59) | CHRM3 | |
| SCHEMBL2126740 | 0.84 | CYP2B6 (0.59) | CHRM3 | |
| SCHEMBL4444477 | 0.84 | CYP2B6 (0.59) | CHRM3 | |
| SCHEMBL2127676 | 0.84 | CYP2B6 (0.59) | CHRM3 | |
| Hydrochloric Acid SCHEMBL8691034 | 0.83 | CHRM3 (0.43) | CHRM3KMT2ACHRM1CHRM4CHRM5 | |
| SCHEMBL27817328 | 0.82 | CHRM3 (0.57) | CHRM3MEN1KMT2ACHRM1ALDH1A1 | |
| SCHEMBL18284663 | 0.81 | SIGMAR1 (0.45) | CHRM3MEN1KMT2ACHRM1CHRM4 | |
| SCHEMBL3312757 | 0.81 | SMN1; SMN2 (0.58) | CHRM3KMT2AALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |