Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10285 | 0.90 | KMT2A (0.36) | KMT2ATARDBPNSD2KDM4EPSEN1 | |
| SCHEMBL2657376 | 0.88 | KDM4E (0.38) | KMT2ATARDBPPDE4APDE4BPDE4C | |
| SCHEMBL30701348 | 0.87 | KMT2A (0.41) | KMT2ATARDBPNAMPT | |
| Hydrochloric Acid SCHEMBL27002611 | 0.86 | KDM4E (0.36) | KMT2ATARDBPPDE4APDE4BPDE4C | |
| SCHEMBL26603825 | 0.83 | — | — | |
| SCHEMBL2195114 | 0.82 | GLA (0.34) | NSD2 | |
| SCHEMBL9186 | 0.81 | KMT2A (0.35) | KMT2ATARDBPPDE4APDE4BPDE4C | |
| SCHEMBL23085402 | 0.80 | ALDH1A1 (0.35) | PDE4APDE4BPDE4CPDE4DNSD2 | |
| SCHEMBL25434640 | 0.79 | KMT2A (0.41) | KMT2ATARDBPPSEN1PSEN2APH1B | |
| SCHEMBL20919435 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |