Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.54 |
| ▸ | MITF | O75030 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698235 | 0.88 | GAA (0.64) | GAACHRM1MITFALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14126546 | 0.86 | GAA (0.62) | GAACHRM1MITFALDH1A1SMN1; SMN2 | |
| SCHEMBL2739199 | 0.85 | MEN1 (0.53) | GAACHRM1ALDH1A1HTTPOLB | |
| SCHEMBL8223521 | 0.85 | MEN1 (0.53) | GAACHRM1ALDH1A1HTTPOLB | |
| SCHEMBL30705384 | 0.84 | CHRM1 (0.51) | GAACHRM1ALDH1A1HTTLMNA | |
| SCHEMBL14126889 | 0.84 | GAA (0.59) | GAACHRM1MITFALDH1A1SMN1; SMN2 | |
| SCHEMBL30771327 | 0.82 | GAA (0.57) | GAACHRM1MITFALDH1A1SMN1; SMN2 | |
| SCHEMBL19932302 | 0.82 | GAA (0.57) | GAACHRM1MITFALDH1A1SMN1; SMN2 | |
| SCHEMBL31063697 | 0.81 | GAA (0.42) | GAACHRM1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL30365759 | 0.79 | GAA (0.43) | GAACHRM1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |