Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771243 | 0.88 | CHRM1 (0.55) | CHRM1SLC1A2GAALMNATP53 | |
| SCHEMBL28068532 | 0.88 | MITF (0.48) | CHRM1LMNAKCNH2ALDH1A1HTT | |
| SCHEMBL31724098 | 0.86 | CHRM1 (0.50) | CHRM1SLC1A2GAALMNATP53 | |
| SCHEMBL26698264 | 0.84 | GAA (0.60) | CHRM1GAALMNAALDH1A1HTT | |
| SCHEMBL18390276 | 0.80 | GAA (0.68) | CHRM1SLC1A2GAALMNATP53 | |
| SCHEMBL3641753 | 0.77 | SLC1A2 (0.62) | CHRM1SLC1A2LMNATP53MAPT | |
| SCHEMBL2436131 | 0.76 | SMN1; SMN2 (0.49) | GAALMNATP53THRBALDH1A1 | |
| SCHEMBL29931638 | 0.76 | SMN1; SMN2 (0.49) | GAALMNATP53THRBALDH1A1 | |
| SCHEMBL28030353 | 0.76 | LMNA (0.45) | LMNAALDH1A1HPGDHTT | |
| SCHEMBL2739199 | 0.76 | MEN1 (0.53) | CHRM1GAATP53KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098765-A | Heterocyclic derivatives as Janus kinase inhibitors | 奇斯药制品公司 | 2023-11-21 | — | — | CN | disclosed |