Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.41 |
| ▸ | GCG | P01275 | 9/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | GIPR | P48546 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720038 | 0.88 | GCGR (0.53) | GCGRGCGGLP1RGIPR | |
| SCHEMBL720571 | 0.88 | GCGR (0.53) | GCGRGCGGLP1RGIPR | |
| SCHEMBL718203 | 0.85 | GCGR (0.45) | GCGRGCGTP53LMNAMAPT | |
| SCHEMBL719279 | 0.84 | GCGR (0.49) | GCGRGCGGLP1RGIPR | |
| SCHEMBL719280 | 0.83 | GCGR (0.42) | GCGRGCGTP53PDE7ACXCR4 | |
| SCHEMBL718249 | 0.83 | RCE1 (0.44) | GCGRTP53NPC1RAB9APDE7A | |
| SCHEMBL720764 | 0.82 | RCE1 (0.46) | GCGRTP53POLBNPC1RAB9A | |
| SCHEMBL717966 | 0.82 | GCGR (0.48) | GCGRGCGNPC1RAB9AGLP1R | |
| SCHEMBL720271 | 0.81 | ALDH1A1 (0.41) | TP53LMNANPC1MAPTRXFP1 | |
| SCHEMBL718454 | 0.77 | GCGR (0.38) | GCGRGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |