Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 14/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502648 | 0.93 | DDB1 (0.57) | DDB1CRBN | |
| SCHEMBL23832613 | 0.89 | DDB1 (0.59) | DDB1CRBN | |
| SCHEMBL22502647 | 0.89 | CRBN (0.58) | DDB1CRBN | |
| SCHEMBL26699679 | 0.89 | CRBN (0.60) | DDB1CRBN | |
| SCHEMBL22526656 | 0.87 | CRBN (0.62) | DDB1CRBN | |
| SCHEMBL29651793 | 0.87 | CRBN (0.62) | DDB1CRBN | |
| SCHEMBL21997435 | 0.87 | CRBN (0.56) | DDB1CRBN | |
| SCHEMBL23832546 | 0.86 | CRBN (0.52) | DDB1CRBN | |
| SCHEMBL23541289 | 0.86 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL23540861 | 0.86 | DDB1 (0.52) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226950-A1 | PEPTIDOMIMETIC STAT PROTEIN DEGRADER, COMPOSITION AND USE THEREOF | 杭州和正医药有限公司 | 2023-11-30 | — | — | WO | disclosed |
| CN-117126231-A | Peptoid STAT protein degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-11-28 | — | — | CN | disclosed |