Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4546572 | 0.80 | NFATC1 (0.42) | P2RX7SLC6A2JAK2FLT1KDR | |
| SCHEMBL28506253 | 0.80 | SLC6A4 (0.54) | BRD4MEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL3229613 | 0.76 | SLC6A2 (0.53) | P2RX7ALDH1A1SLC6A2FLT1KDR | |
| SCHEMBL3225503 | 0.76 | SLC6A2 (0.72) | P2RX7SLC6A2SLC6A4 | |
| SCHEMBL30167772 | 0.74 | NAMPT (0.45) | ALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL173305 | 0.74 | NAMPT (0.45) | ALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL31751759 | 0.73 | CDC7 (0.41) | P2RX7SLC6A2 | |
| SCHEMBL27637862 | 0.70 | RAPGEF4 (0.37) | SLC6A2FLT1KDR | |
| SCHEMBL18003159 | 0.69 | CYP2A6 (0.53) | BRD4ALDH1A1TDP1MEN1HPGD | |
| SCHEMBL1150401 | 0.68 | FGFR1 (0.53) | ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4265613-A1 | BENZENE RING COMPOUND AND USE THEREOF | Nanjing Shijiang Medicine Technology Co., Ltd (CN) | 2023-10-25 | — | — | EP | disclosed |