Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 19/20 | 0.83 |
| ▸ | HSD17B2 | P37059 | 17/20 | 0.75 |
| ▸ | HPGDS | O60760 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31475 | 0.91 | HSD17B1 (1.00) | HSD17B1HSD17B2HPGDS | |
| SCHEMBL24263 | 0.86 | HSD17B1 (1.00) | HSD17B1HSD17B2 | |
| SCHEMBL22709 | 0.85 | HSD17B1 (1.00) | HSD17B1HSD17B2HPGDS | |
| SCHEMBL30431 | 0.83 | HSD17B1 (1.00) | HSD17B1HSD17B2 | |
| SCHEMBL22898 | 0.82 | HSD17B1 (1.00) | HSD17B1HSD17B2 | |
| SCHEMBL23443 | 0.81 | HSD17B1 (1.00) | HSD17B1HSD17B2HPGDS | |
| SCHEMBL22550 | 0.80 | HSD17B1 (0.88) | HSD17B1HSD17B2 | |
| SCHEMBL31434 | 0.78 | HSD17B1 (0.79) | HSD17B1HSD17B2 | |
| SCHEMBL24752 | 0.77 | HSD17B1 (1.00) | HSD17B1HSD17B2 | |
| SCHEMBL31075 | 0.77 | HSD17B1 (0.82) | HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339871-A1 | COMPOUNDS AND METHODS OF MODULATING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | METREA BIOSCIENCES INC (US) | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339871-A1 | COMPOUNDS AND METHODS OF MODULATING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | HSD17B1, HSD17B13, HSD17B11 | HSD17B1 1/4885HSD17B2 4/4885HPGDS 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.