Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29194913 | 0.85 | PSMB8 (0.46) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL28332572 | 0.82 | PSMB8 (0.58) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL30179604 | 0.82 | PSMB8 (0.58) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL6014082 | 0.81 | PSMB8 (0.57) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL29194931 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAKMT2AHTT | |
| SCHEMBL11195336 | 0.78 | PSMB8 (0.53) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL12257976 | 0.77 | PSMB8 (0.64) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL11204586 | 0.77 | PSMB8 (0.51) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL3595617 | 0.76 | ALDH1A1 (0.67) | PSMB8PSMB5CA12CA1CA2 | |
| SCHEMBL30149949 | 0.76 | ALDH1A1 (0.67) | PSMB8PSMB5CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447319-B1 | RUBBER CRAWLER | BRIDGESTONE CORP (JP) | 2017-03-08 | — | — | EP | disclosed |
| US-8530549-B2 | Rubber crawler | BRIDGESTONE CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20120108738-A1 | RUBBER CRAWLER | BRIDGESTONE CORPORTATION (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2447319-A1 | RUBBER CRAWLER | Bridgestone Corporation (JP) | 2012-05-02 | — | — | EP | disclosed |