Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 3/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524313 | 0.74 | CSNK1D (0.48) | CSNK1DCSNK1EMAPK14HTR3AUGCG | |
| SCHEMBL25268493 | 0.74 | MAPK14 (0.33) | CSNK1DMAPK14HTR3AUGCGTHRB | |
| SCHEMBL25220259 | 0.72 | MAPK14 (0.46) | CSNK1DCSNK1EMAPK14HTR3AUGCG | |
| SCHEMBL14844925 | 0.71 | MAPK14 (0.38) | CSNK1DCSNK1EMAPK14 | |
| SCHEMBL24349043 | 0.69 | CSNK1D (0.46) | CSNK1DCSNK1A1CSNK1ETNIKMAPK14 | |
| SCHEMBL14844873 | 0.69 | THRB (0.53) | CSNK1DCSNK1EMAPK14THRBTGFBR1 | |
| SCHEMBL24553877 | 0.69 | CSNK1D (0.43) | CSNK1DCSNK1E | |
| SCHEMBL17373680 | 0.68 | THRB (0.49) | CSNK1DCSNK1EMAPK14THRBTGFBR1 | |
| SCHEMBL14844882 | 0.68 | THRB (0.52) | CSNK1DCSNK1EMAPK14THRBTGFBR1 | |
| SCHEMBL24565991 | 0.68 | CSNK1D (0.40) | CSNK1DCSNK1A1CSNK1ETNIKMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-26 | — | — | US | disclosed |
| EP-4214214-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339970-A1 | CASEIN KINASE 1 DELTA MODULATORS | CSNK1D, CSNK1A1, CSNK1G1 | CSNK1D 1/4885CSNK1A1 2/4885CSNK1E 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.