Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.74 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982268 | 1.00 | UPP1 (0.74) | UPP1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL8053414 | 1.00 | UPP1 (0.74) | UPP1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL2671532 | 1.00 | UPP1 (0.74) | UPP1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL13376174 | 0.89 | UPP1 (0.72) | UPP1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL37456 | 0.89 | UPP1 (0.72) | UPP1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL37457 | 0.89 | UPP1 (0.72) | UPP1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL12800214 | 0.89 | UPP1 (0.72) | UPP1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL17106654 | 0.89 | UPP1 (0.59) | UPP1ALDH1A1KMT2AGAAHPGD | |
| SCHEMBL5182023 | 0.89 | UPP1 (0.59) | UPP1ALDH1A1KMT2AGAAHPGD | |
| SCHEMBL6273837 | 0.89 | UPP1 (0.76) | UPP1CHRNB2CHRNA5CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790252-B2 | 2-fluorinated riboses and arabinoses and methods of use and synthesis | CORNELL UNIVERSITY (US) | 2017-10-17 | — | — | US | disclosed |
| US-20120108535-A1 | 2-FLUORINATED RIBOSES AND ARABINOSES AND METHODS OF USE AND SYNTHESIS | CORNELL UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| EP-0635517-B1 | Process for Producing 1-(2'-deoxy-beta-D-erythropentofuranosyl)-5-trifluoromethyluracil Derivatives | MITSUI CHEMICALS INC (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0635517-A1 | Process for Producing 1-(2'-deoxy-beta-D-erythropentofuranosyl)-5-trifluoromethyluracil Derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108535-A1 | 2-FLUORINATED RIBOSES AND ARABINOSES AND METHODS OF USE AND SYNTHESIS | SLC2A2, SLC29A2, DERA | UPP1 369/4885CHRNB2 4094/4885CHRNA5 3473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.