Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sufentanil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 4/20 | 1.00 |
| ▸ | SLC22A1 | O15245 | 1/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 1/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sufentanil SCHEMBL27722103 | 1.00 | OPRM1 (1.00) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL780198 | 0.99 | OPRM1 (0.98) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL28438312 | 0.99 | OPRM1 (0.98) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL28432948 | 0.99 | OPRM1 (0.98) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL2727222 | 0.98 | OPRM1 (0.96) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL28429544 | 0.95 | OPRM1 (0.91) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL28429542 | 0.95 | OPRM1 (0.91) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL28433888 | 0.95 | OPRM1 (0.90) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL28429546 | 0.94 | OPRM1 (0.88) | OPRM1SLC22A1ABCB1OPRD1OPRK1 | |
| Sufentanil SCHEMBL6057143 | 0.92 | OPRM1 (0.85) | OPRM1SLC22A1ABCB1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 27542 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122075410-A | Dry powder composition for intranasal delivery | — | 2026-05-26 | — | — | CN | claimed |
| CN-122087518-A | Method for classifying anesthetic drugs by using neural network | — | 2026-05-26 | — | — | CN | claimed |
| US-20260132115-A1 | SUBSTITUTED 3-FLUOROBENZENEPROPANOATE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | TIANJIN GUDUI BIO PHARM CO LTD (CN) | 2026-05-14 | — | — | US | claimed |
| CN-122005659-A | Pharmaceutical composition for treating burns and scalds in intensive care and preparation method thereof | 养系列(山东)生物科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4724049-A1 | MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF | Catalent Ontario Limited (CA) | 2026-04-15 | — | — | EP | claimed |
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| EP-4719552-A1 | INDUCTION OF GENERAL ANESTHESIA IN ADULTS UNDERGOING ELECTIVE SURGERY | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2026-04-08 | — | — | EP | claimed |
| US-12594388-B2 | Device to deliver a predetermined amount of a substance to a natural orifice of the body | APTARGROUP, INC. (US) | 2026-04-07 | — | — | US | claimed |
| US-20260076896-A1 | CONTINUOUS OR PERIODICAL TRANSDERMAL DELIVERY OF EXOGENOUS MOLECULE | KIFFIK BIOMEDICAL INC (US) | 2026-03-19 | — | — | US | claimed |
| WO-1991015492-A1 | NOVEL PIPERIDIN-4-SPIRO-OXIRANES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1991-10-17 | — | — | WO | claimed |
| WO-1991008795-A2 | IMPROVED IONTOPHORETIC DELIVERY METHOD | ALZA CORPORATION (US) | 1991-06-27 | — | — | WO | claimed |
| EP-0200490-B1 | COMPOSITIONS FOR NONINVASIVE ADMINISTRATION OF SEDATIVES, ANALGESICS, AND ANESTHETICS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1991-03-20 | — | — | EP | claimed |
| US-4927408-A | For placement on a body surface/delivering agent through | ALZA CORPORATION (US) | 1990-05-22 | — | — | US | claimed |
| US-4917676-A | CONTROLLED DRUG DELIVERY | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | claimed |
| US-4911707-A | Monolithic user-activated transdermal therapeutic system | CIBA-GEIGY CORPORATION (US) | 1990-03-27 | — | — | US | claimed |
| US-4822802-A | TRANSDERMAL DELIVERY | ALZA CORPORATION (US) | 1989-04-18 | — | — | US | claimed |
| EP-0200490-A2 | Compositions for noninvasive administration of sedatives, analgesics, and anesthetics | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1986-11-05 | — | — | EP | claimed |
| US-4588580-A | Transdermal administration of fentanyl and device therefor | ALZA CORPORATION (US) | 1986-05-13 | — | — | US | claimed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | claimed |