Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26728652 | 1.00 | SLC6A4 (1.00) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 | |
| SCHEMBL15850751 | 0.86 | SLC6A4 (0.80) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 | |
| SCHEMBL15444962 | 0.86 | SLC6A4 (0.80) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 | |
| SCHEMBL14961979 | 0.86 | SLC6A4 (0.80) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 | |
| SCHEMBL15444963 | 0.85 | SLC6A4 (0.98) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 | |
| SCHEMBL26728728 | 0.85 | SLC6A4 (1.00) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 | |
| SCHEMBL15833860 | 0.85 | SLC6A4 (0.98) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 | |
| SCHEMBL15850748 | 0.85 | SLC6A4 (0.98) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 | |
| SCHEMBL15833859 | 0.83 | SLC6A4 (1.00) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 | |
| SCHEMBL26728731 | 0.83 | SLC6A4 (0.84) | SLC6A4OPRM1OPRK1SIGMAR1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348465-A1 | IBOGAINE ANALOGS AS THERAPEUTICS FOR NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348465-A1 | IBOGAINE ANALOGS AS THERAPEUTICS FOR NEUROLOGICAL AND PSYCHIATRIC DISORDERS | CHRNA3, CHRNB3, CHRNA4 | SLC6A4 76/4885OPRM1 33/4885OPRK1 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.