Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 5/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355660 | 0.77 | MME (0.38) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL9911498 | 0.77 | MME (0.38) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL18818920 | 0.77 | TDP1 (0.45) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL15072143 | 0.77 | ACE (0.42) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL19194706 | 0.77 | MME (0.38) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5471350 | 0.77 | RNPEP (0.56) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL27261261 | 0.76 | SMN1; SMN2 (0.48) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL24259829 | 0.75 | SLC22A6 (0.43) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL19703836 | 0.74 | ECE1 (0.44) | ALDH1A1LMNATDP1MMEGAA | |
| SCHEMBL24270547 | 0.74 | DPP4 (0.44) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215740-A1 | IMMUNOMODULATORY ANTIBODY-DRUG CONJUGATES | SEAGEN INC. (US) | 2023-11-09 | — | — | WO | disclosed |